Metabolic Investigations of the Molecular Mechanisms Associated with Parkinson’s Disease
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منابع مشابه
Metabolic Investigations of the Molecular Mechanisms Associated with Parkinson’s Disease
Parkinson's disease (PD) is a neurodegenerative disorder characterized by fibrillar cytoplasmic aggregates of α-synuclein (i.e., Lewy bodies) and the associated loss of dopaminergic cells in the substantia nigra. Mutations in genes such as α-synuclein (SNCA) account for only 10% of PD occurrences. Exposure to environmental toxicants including pesticides and metals (e.g., paraquat (PQ) and manga...
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ژورنال
عنوان ژورنال: Metabolites
سال: 2017
ISSN: 2218-1989
DOI: 10.3390/metabo7020022